Seren Aitchison
Computational biology · bioinformatics · medicinal chemistry
serenaitchison.com · · github.com/seren-aitchison
Profile
Education
2022 – 2025
BSc Medicinal Chemistry — Cardiff University
Second Class Honours (Upper Division), 2:1
Dissertation (40 credits): Catalytic Synthesis and Characterisation of a Biobased Heterocyclic Scaffold with Medicinal Potential. Independent research covering catalytic synthesis from furfural, comparison of Amberlyst-26, γ-alumina and calcium oxide catalysts, analytical characterisation by TGA, TEM and GC, and molecular docking of the resulting scaffold.
Coursework: medicinal chemistry and molecular design · organic and inorganic chemistry · physical and analytical chemistry · molecular interactions · chemical characterisation · computational chemistry · biological and pharmaceutical principles
Research outputs
Independent computational analyses. Not peer reviewed. Each has a public write-up with stated methods and limitations; repositories marked private can be shared on request.
Software projects
Technical skills
Independent research proposals
Written independently; not undertaken and not supervised.
Writing
- What a UMAP plot does and does not preserve — dimensionality reduction and the limits of visual interpretation
- Why a docking score is not a binding affinity — scoring functions, rigid receptors and honest claims
- Why genome-wide significance is 5 × 10⁻⁸ — multiple testing and reading a QQ plot
- SHAP explains a model, not a mechanism — feature attribution and biological inference
- The reference genome is a sample, not a truth — reference bias in variant calling, and who it affects
- What a gene list is actually for — background sets, annotation bias and redundancy in enrichment testing
Interests and direction
Precision medicine and multi-omics integration; computational genomics and single-cell analysis; computational drug discovery and pharmacogenomics; interpretable machine learning for biological data; translational and spatial biology. Seeking doctoral research or a computational scientist position where chemistry and computation meet.